Before she rose to fame as Alex Russo on Wizards of Waverly Place, Selena Gomez played Gianna on Barney & Friends from 2002 to 2004.
Long before dominating the Disney Channel with Selena, Demi Lovato starred alongside her former bestie as Angela on the children's series.
Another Disney Channel vet, Debby Ryan appeared in the 2007 film Barney: Let's Go to the Firehouse before going on to star on shows like The Suite Life on Deck, Jessie and Insatiable.
Before going on to voice Penny Proud on Disney Channel's The Proud Family—and its Disney+ revival Louder and Prouder—one of Kyla Pratt's earliest roles was Marcella in the 1998 movie Barney's Great Adventure.
Jaren Lewison may be known for his role as Ben Gross on Netflix's Never Have I Ever, but his first-ever TV gig was playing Joshua on Barney & Friends from 2008 to 2009.
Following the trend of Barney kids becoming Disney stars, Madison Pettis briefly appeared as Bridget alongside the purple dinosaur in 2005 and 2006 before appearing in shows like Hannah Montana and Cory in the House, as well as the 2021 film He's All That.
Best known for his roles as Chris Brody on Homeland and Gage on The Walking Dead, Jackson Pace got his start as Adam on Barney & Friends in 2006.